Rotation Radius Dependence of 123I-FP-CIT and 123I-IBZM SPECT Uptake Ratios: A Monte Carlo Study

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[123I]FP-CIT SPECT in atypical degenerative parkinsonism

Parkinson’s disease (PD) is the second most common neurodegenerative disorder [1], yet early accurate diagnosis remains challenging. The estimated prevalence of PD is 0.5–1% in those aged 65–69 years and 1–3% in those aged ≥80 years [1]. Although the clinical diagnosis of PD may be straightforward in cases with a classic presentation [2], accurate distinction between PD and atypical degenerativ...

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Focal 123I-FP-CIT SPECT Abnormality in Midbrain Vascular Parkinsonism

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SPECT Uptake Ratios: A Monte Carlo Study

In dopamine brain SPECT, semiquantitative techniques are in use, mostly for research purposes, to calculate activity uptake in the striatum relative to the background. The measured uptake ratios depend on both acquisition and reconstruction, and one important parameter is the rotation radius of the g-camera detectors, which affects spatial resolution. In brain SPECT research studies, the rotati...

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Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: the [123I]-FP-CIT study group.

OBJECTIVE To evaluate whether visual assessment of [123I]-FP-CIT (DaTSCAN, Nycomed Amersham, plc) single photon emission computerized tomography (SPECT) images can differentiate between parkinsonism and essential tremor (ET). METHODS [123I]-FP-CIT SPECT imaging was conducted in a six-center study of 158 patients with a clinical diagnosis of parkinsonism compared with 27 ET cases and 35 health...

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Standardized Semi-Quantitative Evaluation of [123I]FP-CIT SPECT in a Multicenter Study

Background and Purpose: To the best of our knowledge no multicenter studies have been published using standardized semi-quantitative evaluation of [123I]FP-CIT scan (DAT-SPECT). The aims of this study were: 1) to cross-compare semi-quantitative software-assisted evaluations of DAT-SPECTs performed in three centers with different equipments; 2) to assess the accuracy of semi-quantitative evaluat...

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ژورنال

عنوان ژورنال: Journal of Nuclear Medicine Technology

سال: 2012

ISSN: 0091-4916

DOI: 10.2967/jnmt.112.108555